Description

Naturally occurring neuropeptide first identified in the 1970s, studied for promoting delta-wave (deep, slow-wave) sleep without the sedation of typical sleep medications, and for dampening HPA-axis stress signaling (reducing ACTH/cortisol). Its precise receptor mechanism has not been definitively identified. Human data is limited to small, older studies with mixed/modest results; very limited modern human data, not FDA-approved.